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卢翠芬副教授

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姓名:卢翠芬

出生年月:198111

职称职务:副教授

专业方向:有机化学

办公电话:027-50865322

电子邮箱:lucf@hubu.edu.cn

研究领域:功能聚合物制备与应用;不对称合成卢翠芬2

 

教学工作:

1.  本科生:《有机化学实验》、《食品风味化学》

2.  研究生:《现代分析测试方法》(色谱、质谱)

 

承担项目与课题:

1)  PEG/POSS纳米杂化水凝胶复合材料的研制及其在人工心脏瓣膜上的应用(51603064),国家自然科学基金青年科学基金项目,24.0万元,2017.12019.12,主持。

2) 组织引导性生物材料激活干细胞调控心脏瓣膜再生机制研究(31330029),国家自然科学基金重点项目子课题,25.0万元,2014.12018.12,主持。

3) 基质金属蛋白酶响应性POSS-PEG纳米杂化水凝胶的制备及其在人工心脏瓣膜中的应用(SKLBEE2020018)2020年省部共建生物催化与酶工程国家重点实验室开放课题,5.0万元,2020.122012.12,主持。

4) 酶降解且降解性可调的PEG/POSS杂化水凝胶的制备及在人工心脏瓣膜上的应用,2017年有机功能分子合成与应用教育部重点实验室开放基金,4.5万元,2017.102019.9,主持。

5) 季鏻盐树状大分子支载手性催化剂的设计、制备及其应用研究(2016CFB126),湖北省自然科学基金项目,5.0万元,2016.12017.12,主持。

6) 聚合物微球支载环状磺酰胺手性诱导试剂的合成及应用研究,有机功能分子合成与应用教育部重点实验室开放基金,4.3万元,2014.102016.9,主持。

7) 分析检测及未知物成分分析,湖北兴发化工集团股份有限公司,20.0 万元,2018.102020.9,主持。

8) 绿色高效缓蚀阻垢剂的设计、制备及协同效应研究,湖北兴发化工集团股份有限公司,20.0万元,2015.12018.12,主持。

9) PEG键合胶原蛋白,华中科技大学同济医学院附属协和医院,10.0万元,2008.12010.12,主持。

 

代表性成果:

1. Renqi Guo#; Ying Zhou#; Siju Liu; Chuang Li; Cuifen Lu*; Guichun Yang; Junqi Nie; Feiyi Wang; Nianguo Dong; Jiawei Shi*; Anticalcification potential of POSS-PEG hybrid hydrogel as a scaffold material for the development of synthetic heart valve leaflets, ACS Applied Bio Materials, 2021, doi.org/10.1021/acsabm.0c01544.

2. Siju Liu#; Tao Jiang#; Renqi Guo; Chuang Li; Cuifen Lu*; Guichun Yang; Junqi Nie; Feiyi Wang; Xiaofan Yang; Zhenbing Chen*; Injectable and degradable PEG hydrogel with antibacterial performance for promoting wound healing, ACS Applied Bio Materials, 2021, doi.org/10.1021/acsabm.1c00004.

3. Siju Liu#; Renqi Guo#; Chuang Li; Cuifen Lu*; Guichun Yang; Feiyi Wang; Junqi Nie; Chao Ma; Meng Gao; POSS hybrid hydrogels: A brief review of synthesis, properties and applications; European Polymer Journal, 2021, 143: 110180.

4. Cuifen Lu#; Wan Xu#; Harshit Shah#; Bingqing Liu; Wei Xu; Liya Sun; Steven Y. Qian; and Wenfang Sun*; In vitro photodynamic therapy of mononuclear and dinuclear iridium(III) bis(terpyridine) complexes, ACS Applied Bio Materials, 2020, 3, 6865–6875.

5. Siju Liu#; Hong Cao#; Renqi Guo; Heling Li; Cuifen Lu*; Guichun Yang; Junqi Nie; Feiyi Wang*; Nianguo Dong; Jiawei Shi*; Feng Shi; Effects of the proportion of two different cross-linkers on the material and biological properties of enzymatically degradable PEG hydrogels, Polymer Degradation and Stability, 2020, 172: 109067.

6. Heling Li#; Jinchi Dai#; Qi Xu; Cuifen Lu*; Guichun Yang; Feiyi Wang; Junqi Nie; Xingjian Hu; Nianguo Dong*; Jiawei Shi; Synthesis of thiol-terminated PEG-functionalized POSS cross-linkers and fabrication of high-strength and hydrolytic degradable hybrid hydrogels in aqueous phase, European Polymer Journal, 2019, 116: 74–83.

7. Heling Li#; Chungeng Liu#; Qi Xu; Cuifen Lu*; Guichun Yang; Feiyi Wang; Junqi Nie; Xingjian Hu; Nianguo Dong; Jiawei Shi*; Bioengineered three-dimensional scaffolds to elucidate the effects of material biodegradability on cell behavior using POSS-PEG hybrid hydrogels, Polymer Degradation and Stability, 2019, 164: 118–126.

8. Jinrui Shen#; Heling Li#; Cuifen Lu*; Guichun Yang; Feiying Wang; Junqi Nie; Xingjian Hu; Nianguo Dong; Jiawei Shi*; Hydrolytically degradable POSS-PEG hybrid hydrogels prepared in aqueous phase with tunable mechanical properties, swelling ratio and degradation rate, Reactive and Functional Polymers, 2018, 123: 91–96.

9. Jingjing Yu#; Zongtao Liu#; Jinrui Shen; Cuifen Lu*; Xingjian Hu; Nianguo Dong*; Guichun Yang; Zuxing Chen; Junqi Nie; Biodegradable inorganic-organic POSS-PEG hybrid hydrogels as scaffolds for tissue engineering, Macromolecular Materials and Engineering, 2017, 302(11), 1700142.

10. Jingjing Yu; Feng Chen; Xichi Wang; Nianguo Dong*; Cuifen Lu*; Guichun Yang; Zuxing Chen; Synthesis and characterization of MMP degradable and maleimide cross-linked PEG hydrogels for tissue engineering scaffolds, Polymer Degradation and Stability, 2016, 133: 312–320.

 

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