姓名:卢翠芬
出生年月:1981年11月
职称职务:副教授
专业方向:有机化学
办公电话:027-50865322
电子邮箱:lucf@hubu.edu.cn
研究领域:功能聚合物制备与应用;不对称合成
教学工作:
1. 本科生:《有机化学实验》、《食品风味化学》
2. 研究生:《现代分析测试方法》(色谱、质谱)
承担项目与课题:
1) PEG/POSS纳米杂化水凝胶复合材料的研制及其在人工心脏瓣膜上的应用(51603064),国家自然科学基金青年科学基金项目,24.0万元,2017.1~2019.12,主持。
2) 组织引导性生物材料激活干细胞调控心脏瓣膜再生机制研究(31330029),国家自然科学基金重点项目子课题,25.0万元,2014.1~2018.12,主持。
3) 基质金属蛋白酶响应性POSS-PEG纳米杂化水凝胶的制备及其在人工心脏瓣膜中的应用(SKLBEE2020018),2020年省部共建生物催化与酶工程国家重点实验室开放课题,5.0万元,2020.12~2012.12,主持。
4) 酶降解且降解性可调的PEG/POSS杂化水凝胶的制备及在人工心脏瓣膜上的应用,2017年有机功能分子合成与应用教育部重点实验室开放基金,4.5万元,2017.10~2019.9,主持。
5) 季鏻盐树状大分子支载手性催化剂的设计、制备及其应用研究(2016CFB126),湖北省自然科学基金项目,5.0万元,2016.1~2017.12,主持。
6) 聚合物微球支载环状磺酰胺手性诱导试剂的合成及应用研究,有机功能分子合成与应用教育部重点实验室开放基金,4.3万元,2014.10~2016.9,主持。
7) 分析检测及未知物成分分析,湖北兴发化工集团股份有限公司,20.0 万元,2018.10~2020.9,主持。
8) 绿色高效缓蚀阻垢剂的设计、制备及协同效应研究,湖北兴发化工集团股份有限公司,20.0万元,2015.1~2018.12,主持。
9) PEG键合胶原蛋白,华中科技大学同济医学院附属协和医院,10.0万元,2008.1~2010.12,主持。
代表性成果:
1. Renqi Guo#; Ying Zhou#; Siju Liu; Chuang Li; Cuifen Lu*; Guichun Yang; Junqi Nie; Feiyi Wang; Nianguo Dong; Jiawei Shi*; Anticalcification potential of POSS-PEG hybrid hydrogel as a scaffold material for the development of synthetic heart valve leaflets, ACS Applied Bio Materials, 2021, doi.org/10.1021/acsabm.0c01544.
2. Siju Liu#; Tao Jiang#; Renqi Guo; Chuang Li; Cuifen Lu*; Guichun Yang; Junqi Nie; Feiyi Wang; Xiaofan Yang; Zhenbing Chen*; Injectable and degradable PEG hydrogel with antibacterial performance for promoting wound healing, ACS Applied Bio Materials, 2021, doi.org/10.1021/acsabm.1c00004.
3. Siju Liu#; Renqi Guo#; Chuang Li; Cuifen Lu*; Guichun Yang; Feiyi Wang; Junqi Nie; Chao Ma; Meng Gao; POSS hybrid hydrogels: A brief review of synthesis, properties and applications; European Polymer Journal, 2021, 143: 110180.
4. Cuifen Lu#; Wan Xu#; Harshit Shah#; Bingqing Liu; Wei Xu; Liya Sun; Steven Y. Qian; and Wenfang Sun*; In vitro photodynamic therapy of mononuclear and dinuclear iridium(III) bis(terpyridine) complexes, ACS Applied Bio Materials, 2020, 3, 6865–6875.
5. Siju Liu#; Hong Cao#; Renqi Guo; Heling Li; Cuifen Lu*; Guichun Yang; Junqi Nie; Feiyi Wang*; Nianguo Dong; Jiawei Shi*; Feng Shi; Effects of the proportion of two different cross-linkers on the material and biological properties of enzymatically degradable PEG hydrogels, Polymer Degradation and Stability, 2020, 172: 109067.
6. Heling Li#; Jinchi Dai#; Qi Xu; Cuifen Lu*; Guichun Yang; Feiyi Wang; Junqi Nie; Xingjian Hu; Nianguo Dong*; Jiawei Shi; Synthesis of thiol-terminated PEG-functionalized POSS cross-linkers and fabrication of high-strength and hydrolytic degradable hybrid hydrogels in aqueous phase, European Polymer Journal, 2019, 116: 74–83.
7. Heling Li#; Chungeng Liu#; Qi Xu; Cuifen Lu*; Guichun Yang; Feiyi Wang; Junqi Nie; Xingjian Hu; Nianguo Dong; Jiawei Shi*; Bioengineered three-dimensional scaffolds to elucidate the effects of material biodegradability on cell behavior using POSS-PEG hybrid hydrogels, Polymer Degradation and Stability, 2019, 164: 118–126.
8. Jinrui Shen#; Heling Li#; Cuifen Lu*; Guichun Yang; Feiying Wang; Junqi Nie; Xingjian Hu; Nianguo Dong; Jiawei Shi*; Hydrolytically degradable POSS-PEG hybrid hydrogels prepared in aqueous phase with tunable mechanical properties, swelling ratio and degradation rate, Reactive and Functional Polymers, 2018, 123: 91–96.
9. Jingjing Yu#; Zongtao Liu#; Jinrui Shen; Cuifen Lu*; Xingjian Hu; Nianguo Dong*; Guichun Yang; Zuxing Chen; Junqi Nie; Biodegradable inorganic-organic POSS-PEG hybrid hydrogels as scaffolds for tissue engineering, Macromolecular Materials and Engineering, 2017, 302(11), 1700142.
10. Jingjing Yu; Feng Chen; Xichi Wang; Nianguo Dong*; Cuifen Lu*; Guichun Yang; Zuxing Chen; Synthesis and characterization of MMP degradable and maleimide cross-linked PEG hydrogels for tissue engineering scaffolds, Polymer Degradation and Stability, 2016, 133: 312–320.